Impact of COVID-19 infection during the postoperative period in patients who underwent gastrointestinal surgery: a retrospective study.

Purpose: The coronavirus disease 2019 (COVID-19) pandemic has led to significant global casualties. This study examines the postoperative impact of COVID-19 on patients who underwent gastrointestinal surgery, considering their heightened vulnerability to infections and increased morbidity and mortality risk. Methods: This retrospective observational study was conducted at a tertiary center and patients who underwent gastrointestinal surgery between January 2022 and February 2023 were included. Postoperative COVID-19 infection was defined as the detection of severe acute respiratory syndrome coronavirus 2 RNA by RT-PCR within 14 days after surgery. Propensity score matching was performed including age, sex, American Society of Anesthesiology physical status classification, and emergency operation between the COVID-19-negative (-) and -positive (+) groups. Results: Following 1:2 propensity score matching, 21 COVID-19(+) and 42 COVID-19(-) patients were included in the study. In the COVID-19(+) group, the postoperative complication rate was significantly higher (52.4% vs. 23.8%, P = 0.023). Mechanical ventilator requirement, intensive care unit (ICU) admission, and readmission rate did not significantly differ between the 2 groups. The median length of ICU (19 days vs. 4 days, P < 0.001) and hospital stay (18 vs. 8 days, P = 0.015) were significantly longer in the COVID-19(+) group. Patients with COVID-19 had a 2.4 times higher relative risk (RR) of major complications than patients without COVID-19 (RR, 2.37; 95% confidence interval, 1.254-4.467; P = 0.015). Conclusion: COVID-19 infection during the postoperative period in gastrointestinal surgery may have adverse outcomes which may increase the risk of major complications. Preoperative COVID-19 screening and protocols for COVID-19 prevention in surgical patients should be maintained.

Whole Blood Titanium Concentration after Limb Salvage Surgery with Three-Dimensional-Printed Ti6Al4V Implants.

Background: Three-dimensional (3D)-printed customized implants can be fabricated and utilized for all bones with massive bone defects. The main safety issues with 3D-printed implants made of Ti6Al4V alloy are related to the release of metal debris and residual powder. In this study, we investigated the perioperative titanium concentrations in whole blood and peri-implant fluid samples of patients who underwent limb salvage surgery with a 3D-printed Ti6Al4V implant. Methods: Nineteen patients who underwent limb salvage surgery with 3D-printed Ti6Al4V implants were divided into two groups: the serial samples group and the follow-up group. To observe metal distribution and clearance in the body, serial samples of blood and peri-implant fluid from the surgical drain were prospectively collected for five patients in the serial samples group. For the remaining 14 patients who were followed up for more than a year, blood samples were collected only once. Results: In the serial samples group, the mean baseline titanium concentration was 0.78 µg/L (range, 0.1-2.2 µg/L): 3 patients showed peak concentration before the third postoperative month, while 2 patients still showed an increasing pattern at this point. Total titanium mass in the surgical drain showed a wash-out phenomenon in a week, with a significant uniform decrease (p = 0.04). In 14 patients in the follow-up group, the mean titanium concentration in the whole blood was 10.8 µg/L (range, 0.3-36.6 µg/L). For the 14 patients with a long-term follow-up, the aluminum and vanadium concentrations were all negligible. Conclusions: Whole blood titanium concentrations were higher after surgery using 3D-printed implants than after that using conventional orthopedic implants, but markedly lower than in patients with implant failure. None of the patients developed serious clinical adverse effects during follow-up.

Floristic inventory and distribution characteristics of algific talus slopes in a specific area of forest biodiversity in South Korea.

Background: This study conducted a survey for establishing in-situ and ex-situ conservation measures for northern lineage plants that are vulnerable to climate change and for designating Forest Genetic Resource Reserve for 25 algific talus slope sites, which are specific areas of forest biodiversity. The survey was conducted in South Korea within a distance of 50 m to the east, west, north and south from the core area where wind blows to the algific talus slopes. The study was conducted once or twice per season from April 2016 to November 2021. New information: Vascular plants of 25 algific talus slope sites in South Korea included a total of 1,052 taxa of 125 families, 486 genera, 947 species, 23 subspecies, 75 variety and 7 forma. The maximum surveyed area was 0.09 km2, accounting for only 0.00014% of the 62,860 km2 forest area in Korea, but comprise 22.27% of the 4,724 species of vascular plants in Korea. The algific talus slopes are areas rich in forest biodiversity. Six taxa were categorized as endangered, including Paeoniaobovata Maxim. Sixty-seven taxa, including Astilboidestabularis (Hemsl.) Engl.; 58 taxa endemic to the Korean Peninsula, including Weigelasubsessilis (Nakai) L.H. Bailey; and 317 taxa of floristic target plants were categorized as rare plants in the Red list. Further, 181 taxa were identified as northern lineage plants and 32 taxa, including Sillaphytonpodagraria (H. Boissieu) Pimenov, were limestone area plants. Regarding alien plants, 75 taxa, including Oenotherabiennis L., were identified and the naturalization and urbanization rates were 7.13% and 12.12%, respectively. Plants specific to the phytogeography of the 25 algific talus slope sites in this study were Vacciniumvitis-idaea L., Rosakoreana Kom., SyringavillosaVahlsubsp.wolfii (C.K. Schneid.) Jin Y.Chen & D.Y. Hong, Lonicerachrysantha Turcz. ex Ledeb., Tephroserisflammea (Turcz. ex DC.) Holub, among others.

Visual Algorithm of VR E-Sports for Online Health Care.

The need for non-face-to-face online health care has emerged through the era of "untact". However, there is a lack of standardization work and research cases on the exercise effect of immersive content. In this study, the possibility of the exercise effect of VR e-sports among e-sports cases were presented through a visual algorithm analysis. In addition, the evaluation criteria were established. The research method compares and analyzes e-sports cases and VR e-sports cases by applying existing evaluation research cases. It also sets up a new evaluation standard. As for the analysis result, the device immersion method and interaction range were set through an algorithm analysis; FOV and frame immersion were set through typification; the user recognition method and interaction method were set through the visual diagram. Then, each derived result value was quantified and a new evaluation criterion was proposed.

A Novel Model on Reinforce K-Means Using Location Division Model and Outlier of Initial Value for Lowering Data Cost.

Today, semi-structured and unstructured data are mainly collected and analyzed for data analysis applicable to various systems. Such data have a dense distribution of space and usually contain outliers and noise data. There have been ongoing research studies on clustering algorithms to classify such data (outliers and noise data). The K-means algorithm is one of the most investigated clustering algorithms. Researchers have pointed out a couple of problems such as processing clustering for the number of clusters, K, by an analyst through his or her random choices, producing biased results in data classification through the connection of nodes in dense data, and higher implementation costs and lower accuracy according to the selection models of the initial centroids. Most K-means researchers have pointed out the disadvantage of outliers belonging to external or other clusters instead of the concerned ones when K is big or small. Thus, the present study analyzed problems with the selection of initial centroids in the existing K-means algorithm and investigated a new K-means algorithm of selecting initial centroids. The present study proposed a method of cutting down clustering calculation costs by applying an initial center point approach based on space division and outliers so that no objects would be subordinate to the initial cluster center for dependence lower from the initial cluster center. Since data containing outliers could lead to inappropriate results when they are reflected in the choice of a center point of a cluster, the study proposed an algorithm to minimize the error rates of outliers based on an improved algorithm for space division and distance measurement. The performance experiment results of the proposed algorithm show that it lowered the execution costs by about 13-14% compared with those of previous studies when there was an increase in the volume of clustering data or the number of clusters. It also recorded a lower frequency of outliers, a lower effectiveness index, which assesses performance deterioration with outliers, and a reduction of outliers by about 60%.

Beet root (Beta vulgaris) protects lipopolysaccharide and alcohol-induced liver damage in rat.

The purpose of this study was to investigate the protective effects of beet root (Beta vulgaris var. rubra) in lipopolysaccharide (LPS) and alcohol induced liver damage. Beta vulgaris ethanol extract (BVEE) showed good antioxidant activity in the contents of polyphenol and flavonoid compounds, and the electron-donating ability and ABTS+ radical scavenging activity. As for anti-inflammatory effect in RAW 264.7 cells, inhibition rate of nitric oxide production was increased in dose dependent manner. In hepatotoxicity model induced by LPS and alcohol in rat, BVEE significantly decreased serum AST, ALT and γ-GTP concentrations in a dose-dependent manner. The histopathological changes after H&E staining showed that fat accumulation and inflammatory cell infiltration were decreased by BVEE. The collagen fibers around the central lobule observed by Masson's trichrome staining were also decreased by BVEE. In addition, as for the immunohistochemical staining and Transmission electron microscopy, BVEE improved morphological characteristics of damaged liver lesion. The increased mRNA expressions of NF-κB, MAPK1, MAPK3, CYP2E1, and α-SMA were significantly decreased in BVEE treated group. These results indicated that BVEE would have protective effects in hepatotoxicity by altering various indicators related to the liver damage induced by LPS or alcohol.

Correction to: Beet root (Beta vulgaris) protects lipopolysaccharide and alcohol­induced liver damage in rat.

[This corrects the article DOI: 10.1007/s43188-019-00030-4.].

Face Recognition at a Distance for a Stand-Alone Access Control System.

Although access control based on human face recognition has become popular in consumer applications, it still has several implementation issues before it can realize a stand-alone access control system. Owing to a lack of computational resources, lightweight and computationally efficient face recognition algorithms are required. The conventional access control systems require significant active cooperation from the users despite its non-aggressive nature. The lighting/illumination change is one of the most difficult and challenging problems for human-face-recognition-based access control applications. This paper presents the design and implementation of a user-friendly, stand-alone access control system based on human face recognition at a distance. The local binary pattern (LBP)-AdaBoost framework was employed for face and eyes detection, which is fast and invariant to illumination changes. It can detect faces and eyes of varied sizes at a distance. For fast face recognition with a high accuracy, the Gabor-LBP histogram framework was modified by substituting the Gabor wavelet with Gaussian derivative filters, which reduced the facial feature size by 40% of the Gabor-LBP-based facial features, and was robust to significant illumination changes and complicated backgrounds. The experiments on benchmark datasets produced face recognition accuracies of 97.27% on an E-face dataset and 99.06% on an XM2VTS dataset, respectively. The system achieved a 91.5% true acceptance rate with a 0.28% false acceptance rate and averaged a 5.26 frames/sec processing speed on a newly collected face image and video dataset in an indoor office environment.

Trans-tendon suture bridge rotator cuff repair with tenotomized pathologic biceps tendon augmentation in high-grade PASTA lesions.

PURPOSE: The purpose of this study was to evaluate whether trans-tendon suture bridge repair with tenotomized pathologic biceps tendon augmentation improves mid-term clinical outcomes for high-grade partial articular-sided supraspinatus tendon avulsion (PASTA) lesions or not. METHODS: A retrospective review of a consecutive series of arthroscopic trans-tendon suture bridge repair with tenotomized pathologic biceps tendon augmentation was conducted. Total 115 patients (44 men and 71 women) with minimum 2 years follow-up were enrolled in our study. Their mean age was 59.7 ± 7.6 (38-77) years and mean follow-up were 6.9 ± 2.5 (2 ~ 10) years. Clinical assessment and radiological outcomes using post-operative MRI were evaluated at last follow-up. RESULTS: All these tears were high-grade PASTA lesions in which mean cuff tear size (exposed footprint) was anteroposterior length 15.7 ± 6.3 mm (5-25 mm) and mediolateral width 10.1 ± 3.6 mm 6.4 mm (5-16 mm). At last follow-up, mean pain VAS, ASES, UCLA, and SST scores were improved from pre-operative values of 5, 59, 21, and 7 to post-operative values of 1, 84.4, 29.5, and 9.4, respectively (p value < 0.001). ROM such as forward flexion, abduction, and internal rotation to the back were improved from a pre-operative mean of 148° (±24), 144° (±24), L2 (Buttock-T7) to a post-operative mean of 161° (±10), 160.0° (±12), and T12 (L3-T5), respectively (p value < 0.001). Follow-up MRI showed Sugaya classification type I in 24 patients (20.9%), type II in 78 patients (67.8%), type III in 11 patients (9.6%) and type 4 in 2 patients (1.7%) were found. As complications, shoulder stiffness was found in five patients, Popeye deformity in two patients and retear in two patients. Revision surgery of the retear was performed in 2 patients. At the last follow-up, 17% (20/115 patients) reported occasional discomfort at the extremes of range of motion during a heavy work or sports activities. CONCLUSIONS: In high-grade PASTA lesions, arthroscopic trans-tendon suture bridge repair with tenotomized pathologic biceps tendon augmentation could be a useful treatment modality capable of preserving rotator cuff footprint, providing simultaneous biceps tenodesis, inducing better tendon healing and possibly preventing tendon buckling and residual pain of the conventional trans-tendon repair methods. These specific methods showed satisfactory outcomes and decreased residual shoulder discomfort (17%) at mid-term follow-up. LEVEL OF EVIDENCE: Level IV, Retrospective case study.